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What is Sepsis?

Sepsis is a rare but serious reaction to an infection. If you get an infection, your body's immune system responds by trying to fight it. Sepsis is when this immune system response becomes overactive and starts to cause damage to the body itself. It can be hard to tell if you have sepsis. Your child might have a fever or high temperature or just feel very unwell. Sepsis needs to be treated urgently because it can quickly get worse and lead to septic shock (low blood pressure and or fast heart rate).

Who is more at risk of sepsis?

Children who have: 

  • not been immunised
  • recently had surgery, trauma or minor procedures 
  • weak immune systems due to illness or drugs (like chemotherapy)
  • recently had a serious illness (including chicken pox)
  • chronic diseases (children with cerebral palsy, or cystic fibrosis)

Babies:

  • born prematurely
  • younger than 1 year
  • whose mother had an infection while pregnant.

How do I know if my child has sepsis?

If you think your child might have an infection and is more unwell than you expect or is getting worse despite treatment, it could be sepsis.  Sepsis can look like other conditions, for example flu or a chest infection.  Sepsis can be especially hard to spot in babies and young children, children and young people with a learning disability.

The diagnosis of sepsis is based on simple measurements (vital signs) such as temperature, heart rate and blood pressure.

Please see Red-Amber-Green tables for advice on when and where to seek care for your child.

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When should you worry?

RED
RED

If your child has any of the following:

  • Is under 3 months old with temperature more than 38°C or under 36°C (unless fever in the 48 hours following vaccinations and no other red features)
  • Breathing very fast, too breathless to talk, eat or drink 
  • Working hard to breathe, drawing in of the muscles below the ribs, or noisy breathing (grunting)
  • Breathing that stops or pauses
  • Is pale, blue, mottled or feels unusually cold to touch
  • Difficult to wake up, very sleepy or confused
  • Weak, high-pitched cry or can’t be settled
  • Has a fit (seizure)
  • Has a rash that does not go away with pressure (the glass test)

You need urgent help.

Go to the nearest Hospital Emergency (A&E) Department or call 999 - dial 999.

AMBER
AMBER

If your child has any of the following:

  • Is 3-6 months old with temperature 39°C or above (unless fever in the 48 hours following vaccinations and no other red or amber features)
  • Temperature of 38°C or above for more than 5 days or shivering with fever (rigors)
  • Temperature less than 36°C in those over 3 months
  • Breathing a bit faster than normal or working a bit harder to breathe
  • Dry skin, lips or tongue
  • Not had a wee or wet nappy in last 8 hours
  • Poor feeding in babies (less than half of their usual amount)
  • Irritable (Unable to settle them with toys, TV, food or hugs even after their fever has come down)
  • Swelling of a limb or joint
  • Not using or putting weight on an arm, leg, hand or foot.
  • Complaining of severe pain that is not improving with painkillers
  • Has had chickenpox in the past few days and is now getting worse with a high fever or spreading red rash
  • Getting worse and I am still worried

You need to contact a doctor or nurse today.

Please contact your GP surgery or call NHS 111 - dial 111.

If symptoms persist for 4 hours or more and you have not been able to speak to either a member of staff from your GP practice or to NHS 111 staff, recheck that your child has not developed any red features.

AMBER
AMBER
Green
Green

If none of the above features are present

  • Watch them closely for any change and look out for any red or amber symptoms
  • If your child has any other symptoms associated with their fever, you may want to look at the information on sore throat, cough, earache, diarrhoea and vomiting or tummy ache or our other pathways.
  • Additional advice is also available to young families for coping with crying of well babies
  • If your child has a long term condition or disability and you are worried please contact your regular team or follow any plans that they have given you.

Self care

Continue providing your child’s care at home. If you are still concerned about your child, speak to your health visitor, local pharmacist or call NHS 111– dial 111.

Children and young people who are unwell and have a high temperature should stay at home. They can go back to school, college or childcare when they no longer have a high temperature, and they are well enough to attend.

Advice and Guidance

Self care and Prevention

What do I do if I am worried my child has sepsis?
  • Get advice from a doctor or healthcare professional or ring 111
  • Your child will need to be examined and have a set of vital signs measured (temperature, heart rate and blood pressure)

Remember most children with fevers or who are unwell, don’t have sepsis.

Tests

There is no one test to see if your child has sepsis.  The tests to look for the infection will vary depending on their age, symptoms and medical history. They can include blood tests, urine tests, chest X-rays and occasionally lumbar puncture (needle in the back to collect spinal fluid).

Your healthcare team should talk to you about any tests or procedures they would like to do, what will happen and what they are for.

Remember

If you're worried that your child or baby is not getting better, still seems unwell or is not themselves, you should talk to a doctor or other healthcare professional. It is important to ask for advice if you're worried, even if you have already seen a doctor, are still having treatment, or are back home. This is because the problems caused by sepsis can come on very quickly, and you may need more (or different) treatment. You should always feel that you can ask questions at any point in your care.

Symptoms of sepsis - NHS (www.nhs.uk)

Sepsis: what to look out for and what care you should expect (nice.org.uk)

Paediatric-Leaflet.pdf (sepsistrust.org)

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